Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531867 | 0.91 | KIF11 (0.38) | CYP11B1CYP11B2ALDH1A1ESR1ESR2 | |
| SCHEMBL11537344 | 0.89 | CYP19A1 (0.40) | CYP3A4P2RX7KMT2ACYP2C19 | |
| SCHEMBL11539766 | 0.78 | CYP11B1 (0.39) | CYP11B1CYP11B2KCNN4MAPK1ALDH1A1 | |
| SCHEMBL30577371 | 0.73 | CYP11B1 (0.57) | CYP11B1CYP11B2KCNN4MAPK1ALDH1A1 | |
| SCHEMBL11532238 | 0.71 | KIF11 (0.41) | CYP11B1CYP11B2ALDH1A1ESR1ESR2 | |
| SCHEMBL11532016 | 0.69 | CYP19A1 (0.42) | ALDH1A1ALOX15CYP3A4P2RX7KMT2A | |
| SCHEMBL11536568 | 0.69 | LMNA (0.44) | CYP11B1CYP11B2MAPK1MAPTKMT2A | |
| SCHEMBL11535035 | 0.69 | KCNN4 (0.36) | CYP11B1CYP11B2KCNN4MAPK1TAAR1 | |
| SCHEMBL11532465 | 0.68 | MAPT (0.39) | CYP11B1CYP11B2KCNN4ALDH1A1ALOX15 | |
| SCHEMBL11533371 | 0.67 | SMN1; SMN2 (0.38) | CYP11B1CYP11B2KCNN4CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |