Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 12/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 12/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 11/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537335 | 0.82 | LMNA (0.50) | TAS1R3TAS1R1TAS1R2KMT2ALMNA | |
| SCHEMBL11538814 | 0.81 | LMNA (0.52) | TAS1R3TAS1R1TAS1R2KMT2ALMNA | |
| SCHEMBL11536712 | 0.81 | LMNA (0.52) | TAS1R3TAS1R1TAS1R2KMT2ALMNA | |
| SCHEMBL11535600 | 0.81 | LMNA (0.52) | TAS1R3TAS1R1TAS1R2KMT2ALMNA | |
| SCHEMBL11542476 | 0.80 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2KMT2A | |
| SCHEMBL11538275 | 0.79 | LMNA (0.50) | KMT2ALMNA | |
| SCHEMBL11538234 | 0.77 | NPC1 (0.52) | TAS1R3TAS1R1TAS1R2KMT2ALMNA | |
| SCHEMBL11535873 | 0.75 | KMT2A (0.44) | KMT2ALMNA | |
| SCHEMBL4177762 | 0.73 | TAS1R3 (0.67) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10825856 | 0.71 | CHRM4 (0.49) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |