Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537335 | 0.86 | LMNA (0.50) | KMT2ALMNARAB9ANPC1ALDH1A1 | |
| SCHEMBL11535600 | 0.84 | LMNA (0.52) | KMT2AMEN1LMNARAB9ANPC1 | |
| SCHEMBL11538814 | 0.84 | LMNA (0.52) | KMT2AMEN1LMNARAB9ANPC1 | |
| SCHEMBL11536712 | 0.84 | LMNA (0.52) | KMT2AMEN1LMNARAB9ANPC1 | |
| SCHEMBL11538234 | 0.83 | NPC1 (0.52) | KMT2AMEN1LMNARAB9ANPC1 | |
| SCHEMBL11538275 | 0.82 | LMNA (0.50) | KMT2AMEN1LMNARAB9ANPC1 | |
| SCHEMBL11543640 | 0.81 | CA12 (0.43) | CA12CA9RAB9ANPC1ALDH1A1 | |
| SCHEMBL11537657 | 0.75 | TAS1R3 (0.51) | KMT2ALMNA | |
| SCHEMBL11273734 | 0.71 | MEN1 (0.36) | KMT2AMEN1LMNARAB9AGFER | |
| SCHEMBL23573418 | 0.70 | EPHX1 (0.42) | CA12CA9RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |