SCHEMBL1153589

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1152996	0.99	ANPEP (0.38)	ANPEPPSMB11PSMA7PSMB1PSMA1
	SCHEMBL1153012	0.97	ANPEP (0.39)	ANPEPPSMB11PSMA7PSMB1PSMA1
	SCHEMBL1153986	0.95	ANPEP (0.40)	ANPEPPSMB11PSMA7PSMB1PSMA1
	SCHEMBL1153629	0.88	CTSL (0.40)	ANPEPPSEN1PSEN2APH1BNCSTN
	SCHEMBL1152940	0.87	CTSL (0.39)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL1154111	0.86	ANPEP (0.42)	ANPEPMEN1KMT2AMAPTALDH1A1
	SCHEMBL1152498	0.86	PSEN1 (0.41)	ANPEPPSEN1PSEN2APH1BNCSTN
	SCHEMBL1153206	0.85	ANPEP (0.41)	ANPEPSLC6A4SLC6A3MEN1KMT2A
	SCHEMBL1153265	0.84	ANPEP (0.42)	ANPEPMEN1KMT2AALDH1A1TDP1
	SCHEMBL1153031	0.84	KEAP1 (0.35)	KEAP1NFE2L2HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.