Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | THPO | P40225 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539909 | 0.82 | ADRB2 (0.69) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL11537605 | 0.80 | ADRB1 (0.47) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL3713557 | 0.80 | ADRB2 (0.70) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL9753417 | 0.77 | ADRB2 (0.68) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL29390491 | 0.77 | PPARA (0.68) | KMT2AALDH1A1RAB9A | |
| SCHEMBL607642 | 0.77 | PPARA (0.68) | KMT2AALDH1A1RAB9A | |
| SCHEMBL6682295 | 0.75 | ADRB3 (0.56) | ADRB1ADRB3 | |
| SCHEMBL6682291 | 0.75 | ADRB3 (0.56) | ADRB1ADRB3 | |
| SCHEMBL6681803 | 0.74 | ADRB3 (0.55) | ADRB1ADRB3 | |
| Arbutamine SCHEMBL7870502 | 0.74 | ADRB2 (0.58) | ADRB2ADRB1ADRB3ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160036-A | ADRENERGIC STIMULANTS | ALLEN & HANBURYS LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |