Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535960 | 0.80 | ADRB2 (0.53) | ADRB1ADRB3ADRB2LMNAHIF1A | |
| SCHEMBL11539909 | 0.76 | ADRB2 (0.69) | ADRB1ADRB3ADRB2LMNAHIF1A | |
| SCHEMBL29390491 | 0.75 | PPARA (0.68) | PPARASTING1KAT8 | |
| SCHEMBL607642 | 0.75 | PPARA (0.68) | PPARASTING1KAT8 | |
| SCHEMBL7317207 | 0.75 | ADRB2 (0.49) | ADRB1ADRB3ADRB2LMNAHIF1A | |
| Cliropamine SCHEMBL2110690 | 0.72 | ADRB2 (0.49) | ADRB1ADRB3ADRB2LMNAHIF1A | |
| Cliropamine SCHEMBL31741642 | 0.71 | SIGMAR1 (0.50) | ADRB1ADRB3ADRB2LMNAHIF1A | |
| Pyrrolidine SCHEMBL3692249 | 0.70 | TDP1 (0.37) | ADRB1ADRB2LMNAHIF1ASLC6A2 | |
| Pyrrolidine SCHEMBL3692242 | 0.70 | TDP1 (0.37) | ADRB1ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL7381182 | 0.69 | SIGMAR1 (0.57) | ADRB1ADRB3ADRB2LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160036-A | ADRENERGIC STIMULANTS | ALLEN & HANBURYS LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |