Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23002152 | 0.80 | DDB1 (0.50) | MEN1KMT2AUSP2HTR2CL3MBTL1 | |
| SCHEMBL512007 | 0.80 | CYP19A1 (0.48) | MEN1KMT2AUSP2CYP19A1HTR2C | |
| SCHEMBL15874851 | 0.78 | CYP19A1 (0.47) | MEN1KMT2AUSP2CYP19A1HTR2C | |
| SCHEMBL1616886 | 0.78 | CYP19A1 (0.47) | MEN1KMT2AUSP2CYP19A1HTR2C | |
| SCHEMBL30496207 | 0.78 | CYP19A1 (0.47) | MEN1KMT2AUSP2CYP19A1HTR2C | |
| SCHEMBL10615961 | 0.77 | MEN1 (0.46) | MEN1KMT2AUSP2CYP19A1HTR2C | |
| SCHEMBL8398502 | 0.75 | HTR2C (0.47) | MEN1KMT2AUSP2CYP19A1HTR2C | |
| SCHEMBL23003290 | 0.75 | NR3C1 (0.46) | GAA | |
| SCHEMBL21722195 | 0.74 | CASP3 (0.38) | ALDH1A1MAPTTDP1KDM4EGAA | |
| SCHEMBL11475323 | 0.74 | MT-CO2 (0.46) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150135-A | ANALGESICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-17 | — | — | US | disclosed |