Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536611 | 0.80 | MEN1 (0.49) | ALDH1A1KDM4EHSD17B10L3MBTL1HTR2C | |
| SCHEMBL8029062 | 0.78 | DDB1 (0.46) | DDB1CRBNALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2329301 | 0.77 | DDB1 (0.54) | DDB1CRBNALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11475323 | 0.77 | MT-CO2 (0.46) | DDB1CRBNALDH1A1MT-CO2ALOX5 | |
| SCHEMBL4132442 | 0.76 | DDB1 (0.53) | DDB1CRBNALDH1A1KDM4EHSD17B10 | |
| SCHEMBL24815345 | 0.76 | DDB1 (0.53) | DDB1CRBNALDH1A1KDM4EHSD17B10 | |
| SCHEMBL15874850 | 0.76 | DDB1 (0.53) | DDB1CRBNALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29973239 | 0.76 | DDB1 (0.53) | DDB1CRBNALDH1A1KDM4EHSD17B10 | |
| SCHEMBL21452208 | 0.74 | RIPK1 (0.35) | MT-CO2ALOX5HTR2C | |
| SCHEMBL7876855 | 0.73 | DDB1 (0.43) | DDB1CRBNHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778579-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jianhe Pharmaceutical & Technology Co. Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |