Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536267 | 0.87 | HTR7 (0.47) | HTR7HTR1BALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11535586 | 0.81 | LTA4H (0.45) | ALDH1A1KDM4ECHEK1AURKADAPK3 | |
| SCHEMBL11535981 | 0.79 | FGFR1 (0.49) | ALDH1A1KDM4ECHEK1AURKADAPK3 | |
| Hydrochloric Acid SCHEMBL11532587 | 0.78 | FGFR1 (0.48) | ALDH1A1KDM4ECHEK1AURKADAPK3 | |
| SCHEMBL11536152 | 0.73 | FGFR1 (0.48) | ALDH1A1KDM4ESMN1; SMN2CHEK1AURKA | |
| Hydrochloric Acid SCHEMBL11383582 | 0.71 | RET (0.33) | HTR7ALDH1A1KDM4ESMN1; SMN2DRD2 | |
| SCHEMBL6904077 | 0.71 | CHEK1 (0.65) | CHEK1AURKADAPK3JAK2PRKD3 | |
| Hydrochloric Acid SCHEMBL11381747 | 0.70 | RET (0.33) | HTR7ALDH1A1KDM4ESMN1; SMN2CHEK1 | |
| Hydrochloric Acid SCHEMBL11382261 | 0.70 | RET (0.33) | HTR7ALDH1A1KDM4ESMN1; SMN2CHEK1 | |
| Hydrochloric Acid SCHEMBL11533381 | 0.70 | RET (0.32) | HTR7CHEK1AURKADAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150134-A | Aminoalkoxy substituted 9(aryl or aralkyl)-acridines | STERLING DRUG INC. (US) | 1979-04-17 | — | — | US | disclosed |