Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | NPY4R | P50391 | 8/20 | 0.32 |
| ▸ | NPY1R | P25929 | 5/20 | 0.32 |
| ▸ | NPY2R | P49146 | 3/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24158411 | 0.86 | ALOX15 (0.35) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL11535671 | 0.83 | ALOX15 (0.33) | ALOX15MEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL26079406 | 0.79 | ALOX15 (0.37) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL24158519 | 0.79 | ALOX15 (0.37) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL14615959 | 0.78 | SIRT6 (0.44) | SIRT6SIRT1SMN1; SMN2NPY4RNPY1R | |
| SCHEMBL24900018 | 0.78 | SIRT5 (0.49) | SIRT6SIRT1NPY4RNPY1RNPY2R | |
| SCHEMBL1934309 | 0.78 | SIRT5 (0.49) | SIRT6SIRT1NPY4RNPY1RNPY2R | |
| SCHEMBL11535880 | 0.76 | SIRT6 (0.39) | SIRT6SIRT1PAOXCHRM2CHRM4 | |
| SCHEMBL24525821 | 0.76 | SIRT6 (0.38) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL468901 | 0.76 | FOLH1 (0.49) | ALOX15SIRT6SIRT1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134918-A | ENZYME INHIBITORS, ANTIBODY INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1979-01-16 | — | — | US | disclosed |