Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ODC1 | P11926 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533680 | 0.81 | CYP2C9 (0.37) | SIRT6SIRT1DPP4DPP8DPP9 | |
| SCHEMBL11536898 | 0.76 | ALOX15 (0.34) | SIRT6SIRT1PAOXCHRM2CHRM4 | |
| SCHEMBL11230702 | 0.74 | PLA2G2C (0.40) | DPP4DPP8DPP9 | |
| SCHEMBL11532872 | 0.73 | PLA2G2C (0.39) | SIRT6SIRT1PAOXDPP4DPP8 | |
| SCHEMBL11539434 | 0.73 | CPB2 (0.45) | SIRT6SIRT1DPP8DPP9DPP7 | |
| SCHEMBL24520157 | 0.71 | SIRT6 (0.50) | SIRT6SIRT1PAOXCA1CA2 | |
| SCHEMBL159460 | 0.71 | GNPAT (0.55) | SIRT6SIRT1CPB2CA1CA2 | |
| SCHEMBL159459 | 0.71 | GNPAT (0.55) | SIRT6SIRT1CPB2CA1CA2 | |
| SCHEMBL13072059 | 0.71 | PLA2G2C (0.44) | SIRT6SIRT1PAOXDPP4DPP8 | |
| SCHEMBL159461 | 0.71 | GNPAT (0.55) | SIRT6SIRT1CPB2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134918-A | ENZYME INHIBITORS, ANTIBODY INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1979-01-16 | — | — | US | disclosed |