Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11538648 | 0.99 | L3MBTL1 (0.51) | DRD4DRD2DRD3ADRB2ADRB1 | |
| SCHEMBL11541942 | 0.90 | GAA (0.51) | DRD4DRD2ADRB2ADRB1ADRB3 | |
| SCHEMBL11574132 | 0.89 | ADRB1 (0.49) | DRD4DRD2DRD3ADRB2ADRB1 | |
| SCHEMBL11538680 | 0.87 | KMT2A (0.50) | DRD4DRD2DRD3L3MBTL1GAA | |
| SCHEMBL11499199 | 0.86 | DRD4 (0.53) | DRD4DRD2DRD3ADRB2ADRB1 | |
| SCHEMBL11542265 | 0.84 | ADRB2 (0.54) | DRD4DRD2DRD3ADRB2ADRB1 | |
| SCHEMBL11539298 | 0.83 | P2RY1 (0.39) | DRD4DRD2ADRB2ADRB1ADRB3 | |
| SCHEMBL11537535 | 0.83 | DRD4 (0.56) | DRD4DRD2DRD3ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL11544679 | 0.82 | P2RY1 (0.39) | DRD4DRD2ADRB2ADRB1ADRB3 | |
| Mindodilol SCHEMBL2107921 | 0.81 | ADRB2 (0.63) | DRD4DRD2ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |