Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12702906 | 0.85 | CHRM2 (0.34) | ACLYKDM4EMEN1PPARGKMT2A | |
| SCHEMBL1812246 | 0.84 | MAOB (0.41) | ACLYERN1KDM4EMAOBMEN1 | |
| SCHEMBL1476544 | 0.81 | ACLY (0.40) | ACLYMAOBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL812046 | 0.77 | NPC1 (0.41) | ACLYKDM4EMAOBMEN1KMT2A | |
| SCHEMBL3176584 | 0.74 | MAOA (0.41) | ACLYKDM4EMAOBCYP1A2CYP3A4 | |
| SCHEMBL13097105 | 0.72 | ABL1 (0.37) | ACLYKDM4EMAOBKMT2ACYP1A2 | |
| SCHEMBL2434431 | 0.71 | MAOA (0.43) | ACLYMAOBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL810958 | 0.70 | CYP17A1 (0.41) | ACLYKDM4EMAOBCYP19A1CYP11B1 | |
| SCHEMBL6208131 | 0.70 | CYP17A1 (0.39) | ACLYERN1KDM4EMAOBCYP1A2 | |
| SCHEMBL12269931 | 0.70 | LMNA (0.36) | ACLYKDM4EMAOBMEN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606254-B1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| EP-1606254-B1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | FISCHER REINER | 2011-04-21 | — | — | US | disclosed |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | FISCHER REINER | 2011-04-21 | — | — | US | disclosed |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | FISCHER REINER | 2011-04-21 | — | — | US | disclosed |
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
| EP-1606254-A1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | Bayer CropScience AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080962-A1 | 2,4,6-PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | CYP4X1, KDM4E, KCNE1 | ACLY 316/4885ERN1 2587/4885KDM4E 2/4885 |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | CYP4X1, KDM4E, PDHX | ACLY 360/4885ERN1 2748/4885KDM4E 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.