Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12801566 | 0.74 | LMNA (0.53) | GAATDP1ALDH1A1POLBNPC1 | |
| SCHEMBL108862 | 0.73 | LMNA (0.56) | GAATDP1ALDH1A1POLBNPC1 | |
| SCHEMBL11536851 | 0.73 | ALDH1A1 (0.49) | GAATDP1ALDH1A1POLBNPC1 | |
| SCHEMBL6361527 | 0.71 | LMNA (0.50) | GAATDP1ALDH1A1POLBNPC1 | |
| SCHEMBL12292649 | 0.71 | LMNA (0.57) | GAATDP1ALDH1A1POLBNPC1 | |
| SCHEMBL11543815 | 0.71 | LMNA (0.61) | GAATDP1ALDH1A1POLBNPC1 | |
| SCHEMBL11539400 | 0.69 | LMNA (0.48) | GAATDP1ALDH1A1POLBNPC1 | |
| SCHEMBL11265208 | 0.68 | BRD4 (0.42) | GAATDP1ALDH1A1POLBNPC1 | |
| SCHEMBL11537526 | 0.68 | LMNA (0.43) | GAATDP1ALDH1A1POLBNPC1 | |
| SCHEMBL13415875 | 0.68 | MAPT (0.47) | GAATDP1ALDH1A1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |