Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480787 | 0.87 | KMT2A (0.61) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL9402317 | 0.85 | KMT2A (0.59) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL27536602 | 0.84 | KMT2A (0.52) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL7768016 | 0.82 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL3577958 | 0.81 | ALOX5 (0.58) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL9402314 | 0.81 | ALOX5 (0.49) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL7901610 | 0.80 | KMT2A (0.53) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5352590 | 0.79 | ALOX5 (0.56) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL5319337 | 0.78 | KMT2A (0.67) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL10118540 | 0.78 | KMT2A (0.65) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145354-A | Process for preparing 5-acyl-2-(furfurylthio)dihydro-2,5-dialkyl-3- 2H!furanones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-03-20 | — | — | US | disclosed |
| US-4143173-A | Flavoring with 5-acyl-2-(furfurylthio)dihydro-2,5-dialkyl-3-[2H]furanones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4138413-A | DIMERIZING AN A,B-DIKETONE, SULFIDING | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4126708-A | FLAVORING WITH 2-ACYL-5-SUBSTITUTED THIATETRAHYDROFURAN-4-ONES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4096158-A | Process for preparing 5-acyl-2-(furfurylthio)dihydro-2,5-dialkyl-3-[2H]furanones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4092334-A | ORGANOLEPTIC PROPERTIES, FLAVOR OR AROMA MODIFIERS FOR FOOD, TOBACCO PRODUCTS, CHEWING GUM AND MEDICINALS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4092333-A | 2-Acyl-5-substituted thiatetrahydrofuran-4-ones | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-05-30 | — | — | US | disclosed |