Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 4/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111236 | 0.89 | ACE (0.76) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL528464 | 0.89 | ACE (0.76) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL111235 | 0.89 | ACE (0.76) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL28419446 | 0.88 | ACE (0.74) | ACEPTPN1CA2CA1GPR132 | |
| Hydrochloric Acid SCHEMBL10622640 | 0.88 | ACE (0.74) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL28419447 | 0.88 | ACE (0.74) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL16611507 | 0.85 | ITGB3 (0.62) | ACEPTPN1CA2CA1GPR132 | |
| SCHEMBL16611508 | 0.85 | ITGB3 (0.62) | ACEPTPN1CA2CA1GPR132 | |
| D-Phenylalanine SCHEMBL10761946 | 0.84 | CA2 (0.65) | ACEPTPN1CA2CA1GPR132 | |
| Phenylalanine SCHEMBL10760080 | 0.84 | CA2 (0.65) | ACEPTPN1CA2CA1GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151198-A | Resolution of N-acyl-DL (+)-phenylalanines | AMERICAN CYANAMID COMPANY (US) | 1979-04-24 | — | — | US | disclosed |