Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259925 | 0.95 | KDM4E (0.54) | KDM4ELMNADRD2NPSR1PTGS1 | |
| SCHEMBL11247004 | 0.94 | PTGS2 (0.47) | KDM4ELMNADRD2NPSR1PTGS1 | |
| SCHEMBL3495616 | 0.90 | ALDH1A1 (0.53) | KDM4ELMNANPSR1PTGS1PTGS2 | |
| SCHEMBL11399825 | 0.85 | LMNA (0.53) | KDM4ELMNADRD2NPSR1PTGS1 | |
| SCHEMBL11390332 | 0.82 | ALDH1A1 (0.51) | KDM4ELMNANPSR1PTGS1PTGS2 | |
| SCHEMBL11400405 | 0.77 | MEN1 (0.52) | KDM4ELMNANPSR1PTGS1PTGS2 | |
| SCHEMBL4833579 | 0.76 | ALDH1A1 (0.51) | KDM4ELMNANPSR1PTGS1PTGS2 | |
| SCHEMBL11403987 | 0.76 | LMNA (0.54) | KDM4ELMNANPSR1PTGS1PTGS2 | |
| SCHEMBL9788262 | 0.76 | LMNA (0.48) | KDM4ELMNANPSR1PTGS1PTGS2 | |
| SCHEMBL5907346 | 0.75 | MEN1 (0.44) | KDM4ELMNANPSR1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |