Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788264 | 0.90 | CYP2C9 (0.57) | LMNANPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9788323 | 0.86 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19PTGS1PTGS2 | |
| SCHEMBL10812124 | 0.82 | SRC (0.44) | LMNANPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9005750 | 0.79 | KMT2A (0.48) | LMNANPSR1PTGS2NPC1RAB9A | |
| SCHEMBL10358492 | 0.77 | CYP1A2 (0.58) | LMNANPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11538580 | 0.76 | KDM4E (0.48) | LMNANPSR1PTGS1PTGS2NPC1 | |
| SCHEMBL122191 | 0.76 | NR4A3 (0.51) | LMNANPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10816206 | 0.75 | LMNA (0.44) | LMNANPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4411084 | 0.75 | NR4A3 (0.50) | LMNANPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31276291 | 0.74 | PTGS2 (0.66) | LMNANPSR1CYP1A2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5062880-A | Male plant sterility | MONSANTO COMPANY (US) | 1991-11-05 | — | — | US | disclosed |
| US-4732603-A | ANTIFERTILITY AGENTS | ROHM AND HAAS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| EP-0049971-B1 | SUBSTITUTED PYRIDAZINES, PROCESSES FOR MAKING THEM, THEIR USE AS PLANT GROWTH REGULATORS, AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0049971-A1 | Substituted pyridazines, processes for making them, their use as plant growth regulators, and plant growth regulating compositions containing them | ROHM AND HAAS COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |