Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645708 | 0.84 | CYP2A6 (0.40) | GAACYP1A2CYP2A6ALDH1A1HPGD | |
| SCHEMBL1263565 | 0.84 | MAPT (0.42) | GAAADORA2AATMCYP1A2ALDH1A1 | |
| SCHEMBL31017312 | 0.81 | MAP4K4 (0.41) | ALDH1A1HPGD | |
| SCHEMBL10725453 | 0.78 | KDM4E (0.38) | GAAALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL250652 | 0.77 | KDM4E (0.33) | DHFRTRPA1ALDH1A1HPGDRAB9A | |
| SCHEMBL31017314 | 0.76 | NQO1 (0.31) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28406055 | 0.75 | ADORA2A (0.50) | GAAADORA2ACYP1A2ALDH1A1HPGD | |
| SCHEMBL29068872 | 0.74 | HPRT1 (0.34) | ALDH1A1HPGDHSD17B10MAPK1HIF1A | |
| SCHEMBL11438193 | 0.74 | ALDH1A1 (0.41) | CYP1A2CYP2A6ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11103322 | 0.72 | MPO (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172045-A | Process for the manufacture of 2-stilbenyl-1,2,3-triazoles which contain carboxyl groups, novel 2-stilbenyl-1,2,3-triazoles which contain carboxyl groups and the use thereof as fluorescent brighteners | CIBA-GEIGY CORPORATION (US) | 1979-10-23 | — | — | US | disclosed |