Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533901 | 0.94 | L3MBTL1 (0.44) | L3MBTL1HSD17B10LMNAALDH1A1PKM | |
| SCHEMBL3513374 | 0.71 | CRHBP (0.38) | L3MBTL1HSD17B10ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28708067 | 0.70 | PIK3CD (0.40) | L3MBTL1ADORA2AADORA1PDE10A | |
| SCHEMBL25322712 | 0.69 | L3MBTL1 (0.38) | L3MBTL1HSD17B10LMNAALDH1A1KMT2A | |
| SCHEMBL12457541 | 0.67 | L3MBTL1 (0.46) | L3MBTL1HSD17B10LMNAALDH1A1PKM | |
| SCHEMBL3544311 | 0.67 | L3MBTL1 (1.00) | L3MBTL1HSD17B10LMNAALDH1A1PKM | |
| SCHEMBL7806232 | 0.67 | L3MBTL1 (0.50) | L3MBTL1HSD17B10LMNAALDH1A1PKM | |
| SCHEMBL20153301 | 0.67 | RECQL (0.60) | L3MBTL1HSD17B10ALDH1A1SMN1; SMN2ADORA2A | |
| SCHEMBL20689399 | 0.66 | L3MBTL1 (0.49) | L3MBTL1HSD17B10LMNAALDH1A1PKM | |
| SCHEMBL46328 | 0.66 | L3MBTL1 (0.49) | L3MBTL1HSD17B10LMNAALDH1A1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |