Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538895 | 0.94 | L3MBTL1 (0.50) | L3MBTL1AKR1C3HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL3513374 | 0.72 | CRHBP (0.38) | L3MBTL1HSD17B10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8358646 | 0.66 | AKR1C3 (0.45) | L3MBTL1AKR1C3HSD17B10BRD9ALDH1A1 | |
| SCHEMBL15491817 | 0.66 | AKR1C3 (0.50) | L3MBTL1AKR1C3BRD9ALDH1A1SMN1; SMN2 | |
| SCHEMBL8356124 | 0.66 | AKR1C3 (0.50) | L3MBTL1AKR1C3BRD9ALDH1A1SMN1; SMN2 | |
| SCHEMBL4461794 | 0.65 | AKR1C3 (0.55) | AKR1C3BRD9ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL12491060 | 0.65 | GPR119 (0.46) | L3MBTL1 | |
| SCHEMBL2733065 | 0.65 | ALDH1A1 (0.35) | L3MBTL1AKR1C3HSD17B10BRD9ALDH1A1 | |
| SCHEMBL255160 | 0.64 | AKR1C3 (0.51) | L3MBTL1AKR1C3BRD9ALDH1A1SMN1; SMN2 | |
| SCHEMBL25322712 | 0.64 | L3MBTL1 (0.38) | L3MBTL1AKR1C3HSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4143047-A | 2-SULFINYL AND 2-SULFONYL OXAZOLES | LILLY INDUSTRIES LIMITED (GB) | 1979-03-06 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |