SCHEMBL11539128

SCHEMBL11539128

CCCCC(=O)OC1CC(C)(CC)NC(C)(CCc2ccccc2)C1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.42
ALOX5 P09917 1/20 0.34
PRKCA P17252 7/20 0.33
KDM4E B2RXH2 3/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
HPGD P15428 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
OPRM1 P35372 1/20 0.32
ABL1 P00519 1/20 0.32
RIN1 Q13671 1/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11531744 0.85 GAA (0.36) BCHEGAACYP1A2CYP3A4CYP2D6
SCHEMBL11535386 0.80 CYP19A1 (0.42) GAAMEN1KMT2AHPGDTSHR
SCHEMBL11538893 0.79 RAB9A (0.39) BCHEGAAMEN1KMT2ACYP2C19
SCHEMBL11529993 0.78 PRKCA (0.43) PRKCAKDM4EMEN1KMT2A
SCHEMBL11533957 0.78 PRKCA (0.36) PRKCA
SCHEMBL11536472 0.78 PRKCA (0.40) BCHEPRKCA
SCHEMBL11535644 0.77 PRKCA (0.38) PRKCAKDM4EMEN1KMT2A
SCHEMBL11620440 0.77 PRKCA (0.38) PRKCAKDM4EMEN1KMT2A
SCHEMBL11440691 0.76 PRKCA (0.33) PRKCATSHR
SCHEMBL11531045 0.76 GAA (0.35) GAAOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4141883-A Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives SANKYO COMPANY, LIMITED (JP) 1979-02-27 US disclosed
US-4075165-A 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed