Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CFB | P00751 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962999 | 0.81 | CREBBP (0.44) | NPC1CREBBPMAPK1KMT2AKDM4E | |
| SCHEMBL10593413 | 0.79 | ALDH1A1 (0.48) | ALDH1A1GLAHPGDKMT2AGAA | |
| SCHEMBL16382501 | 0.79 | TSHR (0.43) | ALDH1A1GLAHPGDKMT2AKDM4E | |
| SCHEMBL3567460 | 0.78 | TUBB4A (0.49) | NPC1ALDH1A1CREBBPHPGDKMT2A | |
| SCHEMBL11451085 | 0.77 | RHEB (0.42) | MTORALDH1A1GLACFBHPGD | |
| SCHEMBL16382499 | 0.76 | LMNA (0.54) | ALDH1A1GLAHPGDKDM4EGAA | |
| SCHEMBL6868530 | 0.76 | HPGD (0.55) | NPC1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL11591618 | 0.75 | MAPT (0.55) | NPC1ALDH1A1MAPK1HPGDKMT2A | |
| SCHEMBL6870413 | 0.75 | CREBBP (0.39) | MTORNPC1ALDH1A1CREBBPKMT2A | |
| SCHEMBL11457182 | 0.75 | VDR (0.38) | NPC1ALDH1A1GLAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |