Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.48 |
| ▸ | LAP3 | P28838 | 3/20 | 0.48 |
| ▸ | ACP3 | P15309 | 5/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10384589 | 0.84 | ANPEP (0.48) | ANPEPLAP3ACP3ERAP1ERAP2 | |
| SCHEMBL9232148 | 0.82 | POLB (0.49) | FDPSKMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL1197672 | 0.78 | S1PR2 (0.48) | ANPEPLAP3ACP3ERAP1ERAP2 | |
| SCHEMBL1197675 | 0.78 | ALDH1A1 (0.44) | LAP3KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL7192599 | 0.77 | MEN1 (0.42) | ANPEPLAP3ACP3ERAP1ERAP2 | |
| SCHEMBL11542459 | 0.76 | LAP3 (0.42) | LAP3KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL3425324 | 0.73 | LAP3 (0.46) | ANPEPLAP3ACP3ERAP1ERAP2 | |
| SCHEMBL1655196 | 0.73 | LAP3 (0.46) | ANPEPLAP3ACP3ERAP1ERAP2 | |
| SCHEMBL1197504 | 0.73 | MEN1 (0.46) | ANPEPLAP3ACP3ERAP1ERAP2 | |
| SCHEMBL1198741 | 0.73 | S1PR2 (0.43) | ANPEPLAP3ACP3ERAP1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150223-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
| US-4032521-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | disclosed |