Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848683 | 0.91 | POLB (0.50) | POLBGAALMNAALDH1A1MAPT | |
| SCHEMBL1197675 | 0.85 | ALDH1A1 (0.44) | POLBLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL11540558 | 0.82 | ANPEP (0.48) | GAAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL5007472 | 0.80 | ALDH1A1 (0.49) | POLBGAALMNAALDH1A1MAPT | |
| SCHEMBL12876278 | 0.79 | LMNA (0.46) | POLBGAALMNAALDH1A1MAPT | |
| SCHEMBL12876302 | 0.79 | ALDH1A1 (0.43) | POLBLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL11542459 | 0.74 | LAP3 (0.42) | POLBGAALMNAALDH1A1NPC1 | |
| SCHEMBL14064070 | 0.72 | ALDH1A1 (0.41) | POLBGAALMNAALDH1A1MAPT | |
| SCHEMBL10384589 | 0.72 | ANPEP (0.48) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL1198741 | 0.72 | S1PR2 (0.43) | LMNAALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638577-A1 | Process for the preparation of N-substituted aminoalkylenephosphonic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-15 | — | — | EP | disclosed |