Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541711 | 0.86 | MAPT (0.47) | HTTNPSR1PTPN1PTGS2ALDH1A1 | |
| SCHEMBL11542874 | 0.85 | PTPN1 (0.42) | HTTNPSR1PTPN1PTGS2ALDH1A1 | |
| SCHEMBL11540561 | 0.85 | TSHR (0.45) | HTTALDH1A1RECQLHSD17B10APLNR | |
| SCHEMBL11540070 | 0.82 | NPSR1 (0.46) | HTTNPSR1PTPN1PTGS2ALDH1A1 | |
| SCHEMBL11541058 | 0.81 | ALDH1A1 (0.42) | HTTPTPN1PTGS2ALDH1A1RECQL | |
| SCHEMBL11540274 | 0.81 | NPSR1 (0.47) | HTTNPSR1PTPN1PTGS2ALDH1A1 | |
| SCHEMBL11575819 | 0.80 | HTT (0.40) | HTTNPSR1PTPN1PTGS2ALDH1A1 | |
| SCHEMBL11542615 | 0.77 | NPSR1 (0.46) | HTTNPSR1PTPN1PTGS2BRD4 | |
| SCHEMBL11541055 | 0.77 | NPSR1 (0.46) | HTTNPSR1PTPN1ALDH1A1HSD17B10 | |
| SCHEMBL29206051 | 0.76 | KCNA3 (0.56) | ALDH1A1HSD17B10BRD4TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168312-A | Quinolone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-09-18 | — | — | US | disclosed |