Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12447952 | 0.81 | RAB9A (0.61) | ALDH1A1HSD11B1SMN1; SMN2HPGDLMNA | |
| SCHEMBL12447336 | 0.76 | CCR5 (0.61) | ALDH1A1HSD11B1TSHRSMN1; SMN2HPGD | |
| SCHEMBL12447948 | 0.76 | CCR5 (0.61) | MEN1KMT2AALDH1A1HSD11B1SMN1; SMN2 | |
| SCHEMBL19988362 | 0.73 | HTR2B (0.64) | ALDH1A1HSD11B1SMN1; SMN2CCR5TP53 | |
| SCHEMBL11178698 | 0.73 | ALDH1A1 (0.58) | ALDH1A1HSD11B1TSHRSMN1; SMN2HPGD | |
| SCHEMBL20738593 | 0.73 | KMT2A (0.48) | MEN1KMT2AALDH1A1EPHX2CYP2C19 | |
| SCHEMBL12447717 | 0.72 | NAMPT (0.57) | ALDH1A1SMN1; SMN2HPGDLMNACCR5 | |
| SCHEMBL16785546 | 0.71 | NPC1 (0.54) | KMT2ATSHRSMN1; SMN2TP53NPC1 | |
| SCHEMBL5202689 | 0.70 | HSD11B1 (0.67) | ALDH1A1HSD11B1POLB | |
| SCHEMBL10652514 | 0.70 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1HSD11B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165371-A | ANALGESICS | RESEARCH CORPORATION (US) | 1979-08-21 | — | — | US | disclosed |