Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.61 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | PTPRE | P23469 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988973 | 0.86 | GPR35 (0.65) | GPR35FEN1ALDH1A1PBRM1MEN1 | |
| SCHEMBL11446092 | 0.80 | GPR35 (0.51) | GPR35KDM4EALDH1A1PTPRCPTPN2 | |
| SCHEMBL4362002 | 0.80 | GPR35 (0.51) | GPR35KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL4366763 | 0.80 | GPR35 (0.51) | GPR35ALDH1A1MEN1KMT2APTPN1 | |
| SCHEMBL8645476 | 0.78 | GPR35 (0.68) | GPR35KDM4EALDH1A1CYP1A2MEN1 | |
| SCHEMBL11455527 | 0.78 | GPR35 (0.68) | GPR35KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7748934 | 0.77 | ALDH1A1 (0.46) | FEN1KDM4EALDH1A1LMNAPBRM1 | |
| SCHEMBL22777068 | 0.77 | CXCR2 (0.55) | KDM4EALDH1A1LMNAPBRM1CXCR2 | |
| SCHEMBL4935684 | 0.76 | CA12 (0.50) | GPR35KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL11445356 | 0.76 | GPR35 (0.47) | GPR35KDM4EALDH1A1LMNAPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154961-A | Oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-05-15 | — | — | US | claimed |