Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744206 | 0.83 | PBRM1 (0.60) | ALDH1A1KDM4EMAPTTSHRLMNA | |
| SCHEMBL9840008 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2PBRM1MEN1 | |
| Hydrochloric Acid SCHEMBL8512694 | 0.81 | PBRM1 (0.58) | ALDH1A1KDM4EMAPTTSHRLMNA | |
| SCHEMBL9609179 | 0.80 | POLB (0.53) | ALDH1A1KDM4EGAAMAPTTSHR | |
| SCHEMBL320037 | 0.80 | ALDH1A1 (0.61) | ALDH1A1GLAMAPTTSHRLMNA | |
| SCHEMBL9513469 | 0.79 | KDM4E (0.43) | ALDH1A1KDM4EGLAGAAPOLB | |
| SCHEMBL14454097 | 0.79 | POLB (0.43) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL22520945 | 0.79 | CES2 (0.48) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL3816160 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBPBRM1MEN1 | |
| SCHEMBL8857062 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EGLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241769-B2 | Pyrimidines as PLK inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-07-10 | — | — | US | disclosed |
| JP-2001002687-A | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUT FACTORY INC | 2001-01-09 | — | — | JP | disclosed |