Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 10/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599024 | 1.00 | CYP11B2 (0.47) | CYP11B2GABRA5LCKIDO1TBXAS1 | |
| SCHEMBL29505892 | 1.00 | CYP11B2 (0.47) | CYP11B2GABRA5LCKIDO1TBXAS1 | |
| SCHEMBL29566780 | 0.93 | CYP11B2 (0.43) | CYP11B2GABRA5LCKIDO1TBXAS1 | |
| SCHEMBL28908126 | 0.93 | CYP11B2 (0.43) | CYP11B2GABRA5LCKIDO1TBXAS1 | |
| SCHEMBL29895259 | 0.72 | CYP11B2 (0.41) | CYP11B2GABRA5LCKIDO1TBXAS1 | |
| SCHEMBL29742732 | 0.71 | KDM4E (0.59) | LCKKDM4EALDH1A1GLAGAA | |
| SCHEMBL970053 | 0.71 | KDM4E (0.59) | LCKKDM4EALDH1A1GLAGAA | |
| SCHEMBL5509760 | 0.71 | SLC6A2 (0.39) | CYP11B2LCKHPGDHSD17B10 | |
| SCHEMBL7364851 | 0.71 | GABRA5 (0.39) | CYP11B2GABRA5LCKIDO1 | |
| SCHEMBL29769929 | 0.68 | ALDH1A1 (0.47) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163745-A | ANTIDIABETIC, HYPOGLYCEMIC | PFIZER INC. (US) | 1979-08-07 | — | — | US | disclosed |