Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413930 | 0.83 | NPC1 (0.54) | ALDH1A1HPGDMAPTNPSR1GAA | |
| SCHEMBL11546965 | 0.82 | ALDH1A1 (0.84) | ALDH1A1HPGDMAPTNPSR1GAA | |
| SCHEMBL19957270 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HPGDMAPTNPSR1KMT2A | |
| SCHEMBL11606488 | 0.80 | LMNA (0.68) | ALDH1A1HPGDMAPTNPSR1GAA | |
| SCHEMBL5450035 | 0.79 | ALDH1A1 (0.67) | ALDH1A1HPGDMAPTNPSR1GAA | |
| SCHEMBL5456726 | 0.78 | NPSR1 (0.70) | ALDH1A1MAPTNPSR1GAAKMT2A | |
| SCHEMBL5437947 | 0.77 | SLC6A4 (0.44) | ALDH1A1HPGDMAPTGAAKMT2A | |
| SCHEMBL7035785 | 0.77 | HSD17B1 (0.56) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL21132969 | 0.77 | LMNA (0.47) | ALDH1A1HPGDMAPTNPSR1GAA | |
| SCHEMBL19957380 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |