Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546965 | 0.87 | ALDH1A1 (0.84) | ALDH1A1HPGDGAAMAPTSMN1; SMN2 | |
| SCHEMBL5450418 | 0.81 | ALDH1A1 (0.79) | ALDH1A1HPGDGAAPOLBMAPT | |
| SCHEMBL4141161 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HPGDGAAPOLBMAPT | |
| SCHEMBL29752141 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HPGDGAAPOLBMAPT | |
| SCHEMBL5454882 | 0.80 | ALDH1A1 (0.69) | ALDH1A1HPGDGAAPOLBMAPT | |
| SCHEMBL5452833 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HPGDGAAPOLBMAPT | |
| SCHEMBL19278117 | 0.80 | ALDH1A1 (0.80) | ALDH1A1HPGDGAAPOLBMAPT | |
| SCHEMBL14338700 | 0.80 | MAPT (0.68) | ALDH1A1HPGDGAAPOLBMAPT | |
| SCHEMBL11542802 | 0.79 | ALDH1A1 (0.57) | ALDH1A1HPGDGAAPOLBMAPT | |
| SCHEMBL3047473 | 0.78 | KMT2A (0.54) | ALDH1A1HPGDGAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |