Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540070 | 0.88 | NPSR1 (0.46) | HTTALDH1A1MAPTNPSR1BRD4 | |
| SCHEMBL11540274 | 0.87 | NPSR1 (0.47) | HTTALDH1A1MAPTNPSR1HSD17B10 | |
| SCHEMBL11544638 | 0.86 | THRB (0.45) | HTTALDH1A1MAPTNPSR1BRD4 | |
| SCHEMBL11540447 | 0.85 | POLB (0.45) | HTTALDH1A1MAPTNPSR1BRD4 | |
| SCHEMBL11544065 | 0.84 | PTGS1 (0.40) | HTTALDH1A1MAPTNPSR1HSD17B10 | |
| SCHEMBL11543287 | 0.82 | HPGD (0.50) | ALDH1A1MAPTNPSR1BRD4TP53 | |
| SCHEMBL11543010 | 0.80 | HTT (0.42) | HTTALDH1A1MAPTNPSR1BRD4 | |
| SCHEMBL11541055 | 0.80 | NPSR1 (0.46) | HTTALDH1A1MAPTNPSR1TP53 | |
| SCHEMBL11542615 | 0.80 | NPSR1 (0.46) | HTTNPSR1BRD4TP53PTPN1 | |
| SCHEMBL11538165 | 0.79 | NPSR1 (0.51) | HTTMAPTNPSR1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168312-A | Quinolone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-09-18 | — | — | US | disclosed |