Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081767 | 0.82 | HDAC1 (0.40) | FDPSHDAC1HDAC6DNMT3BLMNA | |
| SCHEMBL29255940 | 0.77 | FDPS (0.42) | FDPSHDAC1HDAC6DNMT3BLMNA | |
| SCHEMBL7592031 | 0.76 | FDPS (0.40) | FDPSHDAC1HDAC6DNMT3BLMNA | |
| SCHEMBL6948592 | 0.74 | FDPS (0.55) | FDPSHDAC1HDAC6DNMT3BLMNA | |
| SCHEMBL9175319 | 0.73 | FDPS (0.38) | FDPSHDAC1HDAC6DNMT3BLMNA | |
| SCHEMBL9177163 | 0.73 | FDPS (0.38) | FDPSHDAC1HDAC6DNMT3BLMNA | |
| SCHEMBL2563784 | 0.73 | FDPS (0.38) | FDPSHDAC1HDAC6LMNAALDH1A1 | |
| SCHEMBL27535766 | 0.72 | FDPS (0.40) | FDPSHDAC1HDAC6DNMT3BLMNA | |
| SCHEMBL28495984 | 0.72 | FDPS (0.43) | FDPSHDAC1HDAC6DNMT3BLMNA | |
| SCHEMBL1650317 | 0.72 | FDPS (0.52) | FDPSHDAC1HDAC6DNMT3BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180576-A | Purines useful for the potentiation of antibiotics | COMMONWEALTH SCIENTIFIC INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1979-12-25 | — | — | US | disclosed |