Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543167 | 0.82 | FDPS (0.42) | HDAC1HDAC6FDPSALDH1A1CYP3A4 | |
| SCHEMBL7592031 | 0.76 | FDPS (0.40) | HDAC1HDAC6FDPSALDH1A1HSD17B10 | |
| SCHEMBL9177163 | 0.75 | FDPS (0.38) | HDAC1HDAC6FDPSALDH1A1ALOX15 | |
| SCHEMBL9175319 | 0.73 | FDPS (0.38) | HDAC1HDAC6FDPSALDH1A1HSD17B10 | |
| SCHEMBL27535766 | 0.71 | FDPS (0.40) | HDAC1HDAC6FDPSALDH1A1CYP3A4 | |
| SCHEMBL27485126 | 0.71 | CYP3A4 (0.45) | ALDH1A1HSD17B10MAPK1ALOX15CYP3A4 | |
| SCHEMBL1371020 | 0.71 | FDPS (0.40) | HDAC1HDAC6FDPSALDH1A1HSD17B10 | |
| SCHEMBL29255940 | 0.70 | FDPS (0.42) | HDAC1HDAC6FDPSALDH1A1CYP3A4 | |
| SCHEMBL2563784 | 0.70 | FDPS (0.38) | HDAC1HDAC6FDPSALDH1A1CYP3A4 | |
| SCHEMBL1408497 | 0.69 | RIPK1 (0.45) | HDAC1HDAC6ALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689545-A4 | MACROCYCLIC AMIDE AND UREA IMMUNOMODULATORS | ABBOTT LAB (US) | 1996-04-24 | — | — | EP | disclosed |
| EP-0689545-A1 | MACROCYCLIC AMIDE AND UREA IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1996-01-03 | — | — | EP | disclosed |