Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | PRCP | P42785 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546166 | 0.99 | ALDH1A1 (0.35) | CHRM2CHRM1ALDH1A1PDK2CYP1A2 | |
| SCHEMBL11543869 | 0.80 | SLC6A2 (0.38) | CHRM2CHRM1ALDH1A1PDK2CYP1A2 | |
| SCHEMBL11545456 | 0.79 | SLC6A2 (0.38) | CHRM2CHRM1ALDH1A1PDK2CYP1A2 | |
| SCHEMBL11289879 | 0.75 | KMT2A (0.33) | CHRM2CHRM1ALDH1A1PDK2CYP1A2 | |
| SCHEMBL11544443 | 0.74 | SLC6A2 (0.40) | CHRM2CHRM1ALDH1A1CYP1A2SIGMAR1 | |
| SCHEMBL11544153 | 0.71 | — | — | |
| SCHEMBL11541733 | 0.70 | MEN1 (0.38) | CHRM2CHRM1PDK2CYP1A2SIGMAR1 | |
| SCHEMBL11544913 | 0.69 | MEN1 (0.39) | CHRM2CHRM1PDK2CYP1A2SIGMAR1 | |
| SCHEMBL11549621 | 0.67 | SIGMAR1 (0.42) | CHRM2CHRM1SIGMAR1KDM4ECYP2D6 | |
| SCHEMBL11546820 | 0.67 | SIGMAR1 (0.42) | CHRM2CHRM1SIGMAR1KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |