Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544580 | 0.81 | L3MBTL1 (0.45) | GAAKDM4ELMNAACP1POLB | |
| SCHEMBL11542270 | 0.80 | MAPT (0.54) | MEN1KMT2AGAAKDM4ENPC1 | |
| SCHEMBL7030133 | 0.79 | KCNH2 (0.48) | MTNR1AMTNR1BMEN1KMT2AKDM4E | |
| SCHEMBL11542872 | 0.79 | RAB9A (0.46) | PTGDR2MEN1KMT2AGAAKDM4E | |
| SCHEMBL11545978 | 0.77 | MCL1 (0.61) | PTGDR2MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL5972977 | 0.77 | HSD17B10 (0.43) | MTNR1AMTNR1BMEN1KMT2AGAA | |
| SCHEMBL25707033 | 0.76 | KDM4E (0.40) | MTNR1AMTNR1BMEN1KMT2AGAA | |
| SCHEMBL11544887 | 0.75 | KDM4E (0.52) | MEN1KMT2AGAAKDM4EPOLB | |
| SCHEMBL11543638 | 0.75 | PON1 (0.45) | KDM4E | |
| SCHEMBL6543877 | 0.74 | HSD17B10 (0.49) | MEN1KMT2AGAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172145-A | ANALGESICS, ANTIPYRETICS | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1979-10-23 | — | — | US | claimed |
| US-4126625-A | ANTIPHLOGISTIC, ANALGESIC | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1978-11-21 | — | — | US | claimed |
| US-4172145-A | ANALGESICS, ANTIPYRETICS | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1979-10-23 | — | — | US | disclosed |
| US-4126625-A | ANTIPHLOGISTIC, ANALGESIC | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1978-11-21 | — | — | US | disclosed |