Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549304 | 0.78 | SLC6A3 (0.31) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11462365 | 0.76 | — | — | |
| SCHEMBL11289919 | 0.72 | HDAC4 (0.32) | — | |
| SCHEMBL11543907 | 0.69 | SLC6A4 (0.38) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11295881 | 0.69 | PGR (0.33) | — | |
| SCHEMBL11543909 | 0.68 | TAAR1 (0.37) | SLC6A4SLC6A3OPRK1LMNAOPRM1 | |
| SCHEMBL11290237 | 0.67 | PGR (0.35) | — | |
| SCHEMBL11544250 | 0.66 | TAAR1 (0.39) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11553286 | 0.66 | HDAC4 (0.31) | — | |
| SCHEMBL11544913 | 0.66 | MEN1 (0.39) | SLC6A4SLC6A3LMNAOPRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |