Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | BAX | Q07812 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680656 | 0.73 | LTA4H (0.60) | LTA4HTSHRLMNASOS1PABPC1 | |
| SCHEMBL23392270 | 0.73 | LTA4H (0.60) | LTA4HTSHRLMNAPGRMAOB | |
| SCHEMBL16890030 | 0.73 | LTA4H (0.60) | LTA4HTSHRPGRMAOBNR1H2 | |
| SCHEMBL7263349 | 0.72 | LTA4H (0.52) | LTA4HTSHRLMNASOS1PABPC1 | |
| SCHEMBL30020579 | 0.71 | LTA4H (0.57) | LTA4HTSHRPGRMAOBNR1H2 | |
| SCHEMBL5434 | 0.71 | LTA4H (0.57) | LTA4HTSHRPGRMAOBNR1H2 | |
| SCHEMBL5776467 | 0.71 | ALDH1A1 (0.44) | TSHRHTTSMN1; SMN2CA1CA2 | |
| Diphenylether SCHEMBL27982791 | 0.70 | LTA4H (0.71) | LTA4HTSHRSOS1PGRMAOB | |
| SCHEMBL9817938 | 0.70 | MAOB (0.55) | LTA4HTSHRPGRMAOBHTT | |
| SCHEMBL7265752 | 0.70 | MAOB (0.55) | LTA4HTSHRPGRMAOBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179563-A | COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |