Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30020579 | 0.98 | LTA4H (0.57) | MAOBLTA4HTSHRPGRABCG2 | |
| SCHEMBL5434 | 0.98 | LTA4H (0.57) | MAOBLTA4HTSHRPGRABCG2 | |
| SCHEMBL9817938 | 0.95 | MAOB (0.55) | MAOBLTA4HTSHRPGRABCG2 | |
| SCHEMBL3839157 | 0.91 | ALDH1A1 (0.54) | MAOBLTA4HTSHRPGREGFR | |
| SCHEMBL3838974 | 0.91 | ALDH1A1 (0.54) | MAOBLTA4HTSHRPGREGFR | |
| SCHEMBL457828 | 0.91 | MAOB (0.54) | MAOBPGRABCG2EGFRKMT2A | |
| SCHEMBL3838956 | 0.88 | SMN1; SMN2 (0.58) | MAOBLTA4HTSHRPGREGFR | |
| SCHEMBL3842164 | 0.88 | MAOB (0.52) | MAOBABCG2EGFRKMT2AMAPT | |
| SCHEMBL3840708 | 0.86 | MAOB (0.55) | MAOBLTA4HTSHRPGREGFR | |
| SCHEMBL30633275 | 0.86 | MAOB (0.55) | MAOBLTA4HTSHRPGREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068738-A1 | PYRROLE DERIVATIVES AS LIGANDS OF MELANOCORTIN RECEPTORS | NEUROCRINE BIOSCIENCES, INC. (US) | 2003-08-21 | — | — | WO | disclosed |