Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540797 | 0.88 | SCN9A (0.46) | SCN9AFPR2LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL11544501 | 0.87 | FFAR1 (0.53) | ESR1MRGPRX4 | |
| SCHEMBL11542488 | 0.87 | HSPB1 (0.48) | LMNASMN1; SMN2NR4A1NR4A2NR4A3 | |
| SCHEMBL11545459 | 0.84 | F2 (0.43) | SCN9AFPR2LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL756150 | 0.84 | MAPT (0.53) | SCN9AFPR2LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL11540799 | 0.81 | SCN9A (0.45) | SCN9AFPR2SMN1; SMN2IGFBP3PTGER4 | |
| SCHEMBL753409 | 0.76 | SCN9A (0.44) | SCN9AFPR2LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL2544053 | 0.76 | SCN9A (0.44) | SCN9AFPR2LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL6938875 | 0.75 | NR4A1 (0.59) | SMN1; SMN2NR4A1NR4A2NR4A3 | |
| SCHEMBL28428071 | 0.75 | NR4A1 (0.59) | SMN1; SMN2NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151302-A | Araliphatic dihalogen compounds composition and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |
| US-4057647-A | Araliphatic dihalogen compounds and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-08 | — | — | US | disclosed |