Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.42 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544620 | 0.88 | FFAR1 (0.48) | F2PLGPRSS1LMNAMAPT | |
| SCHEMBL11543080 | 0.88 | F2 (0.47) | F2PLGPRSS1LMNAMAPT | |
| SCHEMBL11540797 | 0.87 | SCN9A (0.46) | SCN9AFPR2LMNASMN1; SMN2PTGER4 | |
| SCHEMBL11544485 | 0.84 | SCN9A (0.46) | SCN9AFPR2LMNASMN1; SMN2PTGER4 | |
| SCHEMBL4799775 | 0.80 | F2 (0.52) | F2PLGPRSS1LMNAMAPT | |
| SCHEMBL9518987 | 0.80 | SMN1; SMN2 (0.50) | F2PLGPRSS1LMNAMAPT | |
| SCHEMBL4741524 | 0.80 | F2 (0.52) | F2PLGPRSS1LMNAMAPT | |
| SCHEMBL756150 | 0.79 | MAPT (0.53) | SCN9AFPR2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL11540799 | 0.78 | SCN9A (0.45) | SCN9AFPR2MAPTSMN1; SMN2PTGER4 | |
| SCHEMBL11545463 | 0.78 | MAOB (0.48) | F2PLGPRSS1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151302-A | Araliphatic dihalogen compounds composition and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |
| US-4057647-A | Araliphatic dihalogen compounds and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-08 | — | — | US | disclosed |