Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 7/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.38 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29341181 | 0.83 | S100A4 (0.38) | PBRM1KDM4ECA1CA2CA7 | |
| SCHEMBL29341252 | 0.81 | S100A4 (0.37) | PBRM1KDM4ECA1CA2CA7 | |
| SCHEMBL11545783 | 0.79 | HDAC4 (0.37) | CA1CA2CA7CA9 | |
| SCHEMBL8601620 | 0.79 | KDM4E (0.53) | KDM4EMAOAMAOBCA1CA2 | |
| SCHEMBL11542025 | 0.79 | MEN1 (0.38) | MAPTKDM4EALDH1A1CA9OPRD1 | |
| SCHEMBL11547924 | 0.79 | PDE7A (0.42) | ALDH1A1 | |
| SCHEMBL8599412 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1MAOAMAOBCA1 | |
| SCHEMBL8596234 | 0.76 | GRIN1 (0.46) | KDM4EALDH1A1CA1CA2CA7 | |
| SCHEMBL6937210 | 0.75 | MAPT (0.54) | PBRM1MAPTKDM4EALDH1A1MAOA | |
| SCHEMBL11543225 | 0.74 | CYP3A4 (0.45) | MAPTALDH1A1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172093-A | Pharmacodynamically active indan derivatives | AB KABI (SE) | 1979-10-23 | — | — | US | disclosed |