Ethylene Glycol

Ethylene Glycol

SCHEMBL11544664

O=C(CCCCl)c1ccccc1.OCCO

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.64
MAPT P10636 3/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
LMNA P02545 2/20 0.64
HDAC1 Q13547 5/20 0.58
HDAC8 Q9BY41 5/20 0.58
HDAC3 O15379 1/20 0.58
HDAC4 P56524 1/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HDAC2 Q92769 1/20 0.58
HDAC10 Q969S8 1/20 0.58
HDAC11 Q96DB2 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
HDAC9 Q9UKV0 1/20 0.58
HDAC5 Q9UQL6 1/20 0.58
NPC1 O15118 1/20 0.56
CASP3 P42574 1/20 0.56
RAB9A P51151 1/20 0.56
SENP8 Q96LD8 1/20 0.56
SENP7 Q9BQF6 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL318784 0.94 TDP1 (0.72) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL29506825 0.92 TDP1 (0.69) TDP1MAPTL3MBTL1LMNAHDAC1
Ethylene SCHEMBL10973512 0.90 TDP1 (0.67) TDP1MAPTL3MBTL1LMNAHDAC1
Acetic Acid SCHEMBL2763001 0.89 L3MBTL1 (0.64) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL2238406 0.88 TDP1 (0.76) TDP1MAPTL3MBTL1LMNAHDAC1
Butane SCHEMBL27573434 0.87 L3MBTL1 (0.62) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL633401 0.86 TDP1 (0.80) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL2236826 0.86 TDP1 (0.80) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL633948 0.86 TDP1 (0.80) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL9035605 0.84 TDP1 (0.58) TDP1MAPTL3MBTL1LMNAHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4166120-A Analgesic and tranquilizing benzoylpropyl-spiro[dihydrobenzofuran]piperidines and pyrrolidines AMERICAN HOECHST CORPORATION (US) 1979-08-28 US disclosed