Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633948 | 1.00 | TDP1 (0.80) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL2236826 | 1.00 | TDP1 (0.80) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL2238406 | 0.98 | TDP1 (0.76) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL318784 | 0.92 | TDP1 (0.72) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL29506825 | 0.90 | TDP1 (0.69) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL8519287 | 0.89 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL9057671 | 0.89 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL27516050 | 0.89 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| Ethylene SCHEMBL10973512 | 0.88 | TDP1 (0.67) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL7068671 | 0.87 | TDP1 (0.95) | TDP1L3MBTL1MAPTLMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250230478-A1 | COMBINATION OF NUCLEIC ACID SEQUENCES ENCODING PROTEINS DERIVED FROM HELICHRYSUM UMBRACULIGERUM, AND ANY TRANSGENIC CELL, TISSUE, AND ORGANISM COMPRISING SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2025-07-17 | — | — | US | disclosed |
| EP-4584377-A1 | COMBINATION OF NUCLEIC ACID SEQUENCES ENCODING PROTEINS DERIVED FROM HELICHRYSUM UMBRACULIGERUM, AND ANY TRANSGENIC CELL, TISSUE, AND ORGANISM COMPRISING SAME | Yeda Research and Development Co. Ltd. (IL) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024052918-A1 | COMBINATION OF NUCLEIC ACID SEQUENCES ENCODING PROTEINS DERIVED FROM HELICHRYSUM UMBRACULIGERUM, AND ANY TRANSGENIC CELL, TISSUE, AND ORGANISM COMPRISING SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2024-03-14 | — | — | WO | disclosed |
| EP-2536687-A2 | PROCESS FOR SYNTHESIS OF 2-SUBSTITUTED PYRROLIDINES AND PIPERADINES | Novartis AG (CH) | 2012-12-26 | — | — | EP | disclosed |
| US-20120302756-A1 | PROCESS FOR SYNTHESIS OF 2-SUBSTITUTED PYRROLIDINES AND PIPERADINES | NOVARTIS AG (CH) | 2012-11-29 | — | — | US | disclosed |
| US-20120122180-A1 | INCORPORATION OF TYPE III POLYKETIDE SYNTHASES INTO MULTIDOMAIN PROTEINS OF THE TYPE I AND III POLYKETIDE SYNTHASE AND FATTY ACID SYNTHASE FAMILIES | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2012-05-17 | — | — | US | disclosed |
| EP-2419400-A1 | MONOAMINE REUPTAKE INHIBITORS | RESEARCH TRIANGLE INSTITUTE (US) | 2012-02-22 | — | — | EP | disclosed |
| WO-2011103263-A2 | PROCESS FOR SYNTHESIS OF 2-SUBSTITUTED PYRROLIDINES AND PIPERADINES | NOVARTIS AG (CH) | 2011-08-25 | — | — | WO | disclosed |
| US-20110084230-A1 | Process for Synthesizing Organoelemental Compounds | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20080233628-A1 | Incorporation of type III polyketide synthases into multidomain proteins of the type I and III polyketide synthase and fatty acid synthase families | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2008-09-25 | — | — | US | disclosed |
| US-5147881-A | 4-(1,2-BENZISOXAZOLYL)PIPERIDINE ANTIPSYCHOTIC AGENTS | PFIZER INC (US) | 1992-09-15 | — | — | US | disclosed |
| WO-1992008718-A1 | 4-(1,2-BENZISOXAZOLYL)PIPERIDINE ANTIPSYCHOTIC AGENTS | PFIZER INC. (US) | 1992-05-29 | — | — | WO | disclosed |
| US-4891375-A | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds | PFIZER INC. (US) | 1990-01-02 | — | — | US | disclosed |
| EP-0279598-A2 | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds | PFIZER INC. (US) | 1988-08-24 | — | — | EP | disclosed |
| EP-0069536-B1 | PHLOROPHENONE DERIVATIVES, PROCESSES FOR PREPARING SUCH COMPOUNDS, USES AND PHARMACEUTICAL COMPOSITIONS OF PHLOROPHENONE COMPOUNDS | NORISTAN LIMITED (ZA) | 1986-12-17 | — | — | EP | disclosed |
| US-4578520-A | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1986-03-25 | — | — | US | disclosed |
| US-4503256-A | BACTERICIDES, FUNGICIDES | NORISTAN LIMITED (ZA) | 1985-03-05 | — | — | US | disclosed |
| EP-0035228-B1 | TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |
| US-4372953-A | Tetrazole derivatives, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-02-08 | — | — | US | disclosed |
| EP-0069536-A1 | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1983-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110084230-A1 | Process for Synthesizing Organoelemental Compounds | CHRM1, CHRM2, MLX | TDP1 4230/4885L3MBTL1 135/4885MAPT 446/4885 |
| US-20120302756-A1 | PROCESS FOR SYNTHESIS OF 2-SUBSTITUTED PYRROLIDINES AND PIPERADINES | DHPS, ALDH18A1, QDPR | TDP1 4635/4885L3MBTL1 4769/4885MAPT 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.