SCHEMBL5880409

SCHEMBL5880409

CCOP(=O)(Cl)Cl.O=S(=O)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.50
PKM P14618 2/20 0.50
TP53 P04637 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ELANE P08246 2/20 0.44
KMT2A Q03164 1/20 0.44
ESR1 P03372 3/20 0.42
ENPP2 Q13822 1/20 0.41
RAPGEF4 Q8WZA2 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
LMNA P02545 1/20 0.38
CA2 P00918 3/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA9 Q16790 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11547365 0.80 GAA (0.54) GAAPKMELANEKMT2AESR1
SCHEMBL915303 0.80 GAA (0.46) GAAPKMELANEKMT2AESR1
SCHEMBL916528 0.80 GAA (0.46) GAAPKMELANEKMT2AESR1
SCHEMBL11544837 0.80 GAA (0.54) GAAPKMELANEKMT2AESR1
SCHEMBL417833 0.74 GAA (0.65) GAAPKMELANEKMT2ANPSR1
SCHEMBL23919240 0.73 KMT2A (0.51) GAAPKMKMT2AESR1ENPP2
SCHEMBL5880408 0.73 PKM (0.50) GAAPKMELANEKMT2AESR1
SCHEMBL18838 0.73 GAA (0.67) GAAPKMELANEKMT2AENPP2
SCHEMBL29724901 0.73 GAA (0.67) GAAPKMELANEKMT2AENPP2
SCHEMBL3792342 0.73 GAA (0.67) GAAPKMELANEKMT2AENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153925-B2 Condensation polymers from N, N*-disubstituted disulfonamides PEWS R GARTH 2006-12-26 US disclosed
US-20060128924-A1 Novel condensation polymers from N, N*-disubstituted disulfonamides PEWS R G 2006-06-15 US disclosed