Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22204510 | 0.81 | KMT2A (0.61) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL7464495 | 0.81 | KMT2A (0.58) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL29867812 | 0.81 | KMT2A (0.61) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL11543993 | 0.80 | ADORA3 (0.46) | ALDH1A1SMN1; SMN2NPC1GAATDP1 | |
| SCHEMBL18304782 | 0.76 | KMT2A (0.54) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL29867643 | 0.76 | KMT2A (0.54) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL7461294 | 0.75 | KMT2A (0.54) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL22204501 | 0.75 | KMT2A (0.47) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL29867683 | 0.75 | KMT2A (0.47) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL7457669 | 0.74 | KMT2A (0.62) | ALDH1A1KMT2AHPGDMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179561-A | REACTING A 3-DIAZOOXINDOLE WITH A SUBSTITUTED ACETYLENE | E. R. SQUIBB & SONS, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4144218-A | MOLDING MATERIALS | HERCULES INCORPORATED (US) | 1979-03-13 | — | — | US | disclosed |
| EP-0000385-A1 | Thermosetting compositions based on polyarylacetylenes and substituted polyphenylene oxides and resins obtained by curing them | HERCULES INCORPORATED (US) | 1979-01-24 | — | — | EP | disclosed |
| US-4112096-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4076818-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |