SCHEMBL22204501

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29867683	1.00	KMT2A (0.47)	KMT2AMAPTHPGDGAAGFER
	SCHEMBL22204559	0.82	ADORA3 (0.46)	KMT2AMAPTGAAMEN1MAPK1
	SCHEMBL22204494	0.77	FGFR4 (0.61)	KMT2AMAPTHPGDGAAGFER
	SCHEMBL29867447	0.77	FGFR4 (0.61)	KMT2AMAPTHPGDGAAGFER
	SCHEMBL20802144	0.76	ADORA3 (0.42)	KMT2AMAPTHPGDGAAMEN1
	SCHEMBL29867767	0.76	HSD17B10 (0.37)	KMT2AMAPTMEN1MAPK1ALDH1A1
	SCHEMBL28377256	0.75	FGFR4 (0.43)	KMT2AMAPTHPGDMEN1MAPK1
	SCHEMBL20802053	0.75	FGFR4 (0.67)	FGFR4FGFR1FGFR2FGFR3
	SCHEMBL11544944	0.75	ALDH1A1 (0.53)	KMT2AMAPTHPGDGAAGFER
	SCHEMBL7464495	0.75	KMT2A (0.58)	KMT2AMAPTHPGDGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.