Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755165 | 0.79 | ALDH1A1 (0.45) | DGAT1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL236467 | 0.75 | RAB9A (0.64) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL12647972 | 0.74 | DGAT1 (0.48) | DGAT1KDM4ENPC1RAB9AKDR | |
| SCHEMBL12647975 | 0.73 | DGAT1 (0.43) | DGAT1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL12663993 | 0.70 | DGAT1 (0.55) | DGAT1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL29832234 | 0.66 | ALDH1A1 (0.51) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL3403578 | 0.66 | ALDH1A1 (0.51) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL11036757 | 0.66 | KDM4E (0.33) | KDM4EMAPTMEN1GAAKMT2A | |
| SCHEMBL16938414 | 0.66 | GABRP (0.49) | KDM4ENPC1RAB9AGAAKMT2A | |
| SCHEMBL1923453 | 0.66 | CA12 (0.38) | KDM4EMAPTMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166817-A | Penicillins | BEECHAM GROUP LIMITED (GB) | 1979-09-04 | — | — | US | disclosed |