Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547646 | 0.75 | HTR2A (0.58) | CETPHTR2AHTR2BHTR2CSIGMAR1 | |
| SCHEMBL11545201 | 0.75 | SIGMAR1 (0.50) | HTR2AHTR2BHTR2CSIGMAR1LMNA | |
| Hydrochloric Acid SCHEMBL11546088 | 0.74 | HTR2A (0.57) | CETPHTR2AHTR2BHTR2CSIGMAR1 | |
| SCHEMBL17449716 | 0.73 | HTR2A (0.44) | CETPHTR2AHTR2BHTR2CFFAR4 | |
| SCHEMBL8000326 | 0.73 | CSNK1E (0.58) | HTR2ACSNK1EALDH1A1TDP1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9456845 | 0.72 | CSNK1E (0.56) | HTR2ACSNK1EALDH1A1TDP1SIGMAR1 | |
| SCHEMBL13064250 | 0.72 | CETP (0.40) | CETPHTR2CFFAR4ALDH1A1TDP1 | |
| SCHEMBL12300586 | 0.71 | CETP (0.41) | CETPHTR2AHTR2BHTR2CFFAR4 | |
| SCHEMBL5729617 | 0.71 | PNMT (0.44) | CETPHTR2CFFAR4ALDH1A1TDP1 | |
| SCHEMBL11547028 | 0.70 | SIGMAR1 (0.55) | HTR2AHTR2BHTR2CSIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148923-A | 1-(3'-Trifluoromethylthiophenyl)-2-ethylaminopropane pharmaceutical composition and method for treating obesity | SYNTHELABO (FR) | 1979-04-10 | — | — | US | disclosed |
| US-4129598-A | ANOREXIGENIC AGENTS | SYNTHELABO (FR) | 1978-12-12 | — | — | US | disclosed |